Computer-aided detection of early Barrett’s neoplasia using volumetric laser endomicroscopy

Targeting neoplasia using volumetric laser endomicroscopy with laser marking.

Volumetric laser endomicroscopy (VLE) is a recent advanced imaging technology that allows high resolution microstructure imaging of the esophagus and gastric cardia; it has been increasingly used in Europe and the USA [1–3]. The system has been recently upgraded to include a laser marking device that places cautery marks on the mucosa to provide targets for histology. We report a case of an inc...

Early detection of radiographic knee osteoarthritis using computer-aided analysis.

OBJECTIVE To determine whether computer-based analysis can detect features predictive of osteoarthritis (OA) development in radiographically normal knees. METHOD A systematic computer-aided image analysis method weighted neighbor distances using a compound hierarchy of algorithms representing morphology (WND-CHARM) was used to analyze pairs of weight-bearing knee X-rays. Initial X-rays were a...

Computer Aided Detection of Potential Colorectal Neoplasia at CT Colonography

Early Skin Cancer Detection Using Computer Aided Diagnosis Techniques

Skin cancers are cancers that due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types: basal-cell cancer, squamous-cell cancer and melanoma. Among the three melanoma spreads through metastasis, and therefore it has been proved to be very fatal. Melanomas typically occur in the skin and identification of skin cance...

Detection of buried Barrett's glands after radiofrequency ablation with volumetric laser endomicroscopy.

BACKGROUND AND AIMS The prevalence and clinical relevance of buried Barrett's glands (BB) after radiofrequency ablation (RFA) in Barrett's esophagus (BE) are debated. Recent optical coherence tomography studies demonstrated a high prevalence of BBs. Direct histological correlation, however, has been lacking. Volumetric laser endomicroscopy (VLE) is a second-generation optical coherence tomograp...